Journal article
Jacqueline K. Shaia, Neha Sharma, Madhukar Kumar, Jeffrey Chu, Christopher M. Maatouk, Katherine E. Talcott, Rishi P. Singh, Devon A Cohen
Neurology, 2024
Neurology, 2024
Semantic Scholar
DOI
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APA
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Shaia, J. K., Sharma, N., Kumar, M., Chu, J., Maatouk, C. M., Talcott, K. E., … Cohen, D. A. (2024). Changes in Prevalence of Idiopathic Intracranial Hypertension in the United States Between 2015 and 2022, Stratified by Sex, Race, and Ethnicity. Neurology.
Chicago/Turabian
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Shaia, Jacqueline K., Neha Sharma, Madhukar Kumar, Jeffrey Chu, Christopher M. Maatouk, Katherine E. Talcott, Rishi P. Singh, and Devon A Cohen. “Changes in Prevalence of Idiopathic Intracranial Hypertension in the United States Between 2015 and 2022, Stratified by Sex, Race, and Ethnicity.” Neurology (2024).
MLA
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Shaia, Jacqueline K., et al. “Changes in Prevalence of Idiopathic Intracranial Hypertension in the United States Between 2015 and 2022, Stratified by Sex, Race, and Ethnicity.” Neurology, 2024.
BibTeX Click to copy
@article{jacqueline2024a,
title = {Changes in Prevalence of Idiopathic Intracranial Hypertension in the United States Between 2015 and 2022, Stratified by Sex, Race, and Ethnicity.},
year = {2024},
journal = {Neurology},
author = {Shaia, Jacqueline K. and Sharma, Neha and Kumar, Madhukar and Chu, Jeffrey and Maatouk, Christopher M. and Talcott, Katherine E. and Singh, Rishi P. and Cohen, Devon A}
}
Check out a talk of this work presented at the American Academy of Ophthalmology
Abstract
BACKGROUND AND OBJECTIVES With the obesity epidemic within the United States, the prevalence of idiopathic intracranial hypertension (IIH) is predicted to rise. IIH prevalence and racial disparities have rarely been reported in the United States. The purpose of this study was to evaluate the prevalence of IIH in a large national database while stratifying by sex, age, race, and ethnicity.
METHODS This was a cross-sectional epidemiologic evaluation conducted in the TriNetX US Collaborative network using data from 2015 to 2022. Patients with an International Classification of Diseases code of IIH and papilledema or unspecified papilledema were included in the study. Any secondary cause of intracranial hypertension including cerebral neoplasms and hydrocephalus were excluded from the study. IIH trends were later compared with TriNetX cohort obesity trends. Prevalence and prevalence odds ratios (ORs) were calculated in Microsoft Excel and R Studio.
RESULTS Among 85 million patients in this database, a 1.35 times increase in the prevalence of IIH occurred between 2015 and 2022 from 7.3 (95% CI 6.9-7.7) individuals per 100,000 to 9.9 (95% CI 9.5-10.3) individuals per 100,000 in 2022. In 2022, Black female individuals had the highest prevalence of IIH with 22.7 individuals per 100,000 compared with the 13.7 White female individuals per 100,000. Patients aged 11-17 years showed the largest growth of IIH prevalence with female individuals increasing by 10 individuals per 100,000 by 2022. Overall, Black and Hispanic patients had the largest prevalence OR of IIH at 1.66 (95% CI 1.49-1.85) and 1.33 (95% CI 1.14-1.56), respectively, compared with White female patients.
DISCUSSION IIH is a rapidly increasing health care concern for the US population, particularly among adolescent patients. Black and Hispanic female individuals are most predominately affected by this incapacitating disorder.
